Logo-jcvtr

J Cardiovasc Thorac Res. 2024;16(4): 211-221. doi: 10.34172/jcvtr.33230
PMID: 40027370        PMCID: PMC11866776

Review Article

Post-transplant cyclophosphamide-induced cardiotoxicity: A comprehensive review

Azin Alizadehasl 1 ORCID, Bita Shahrami 2,3, Reza Rahbarghazi 4,5, Azam Yalameh Aliabadi 1, Seyedeh Fatemeh Hosseini Jebelli 1, Yasamin Afsari Zonooz 1, Hoda Hakimian 1, Farzaneh Fathi 6, Sara Forati 1 * ORCID, Aysa Rezabakhsh 7 * ORCID

Cited by CrossRef:

1- He W, Feng J, Luo R, Jiang F, Sui X, Hong X. Recent Advances in Understanding the Mechanisms of Therapy-Related Cardiovascular Events in Pediatric Hematologic Malignancies. Rev Cardiovasc Med. 2026;27(4) [Crossref]
2- Woods E, Munjal S, Abidi M, Pantin J, Graves V, Nowak H, Weinstein N, Blankenberger K, Musall K, Prasad P, Goebel W, Johnstone B. Cryopreserved organ donor bone marrow achieves robust engraftment and chimerism in mismatched allogeneic transplantation. Cytotherapy. 2026;28(2):102006 [Crossref]
3- Xu V, Ahmed B, Boleslav B, Mager D, Sparreboom A, Sprowl J, Huang K. Insights and perspectives into the etiology of TKI-induced cardiotoxicity. ASPET Discovery. 2026;2:100025 [Crossref]
4- Ștefan M, Magda L, Vinereanu D. Artificial Intelligence and the Expanding Universe of Cardio-Oncology: Beyond Detection Toward Prediction and Prevention of Therapy-Related Cardiotoxicity—A Comprehensive Review. Diagnostics. 2026;16(3):488 [Crossref]
5- Thukral J, Moudgil P, Sindhwani N, Makkar S, Kaur J, Mann A, Shah R, Kaur H, Agrawal S, Thukral N, Frishman W, Aronow W. Global Longitudinal Strain as a Surveillance Tool in Hematologic Cancer-Related Cardiotoxicity. 2026; [Crossref]
6- Torrent-Rodríguez A, Cascos E, Garcés V, Pérez-López E, Baile-González M, Rodríguez C, Cascón M, Luque M, Esquirol A, Calvo C, Peña-Muñoz F, Fernando I, Ormtegi I, Marín A, Fernández-Luis S, Domínguez-García J, Fernández S, Lorenzo J, de Sanmamed Girón M, Pinedo L, García-Maño L, González-Rodriguez A, Torrado T, Filaferro S, Basalobre P, Ortí G, Rovira M, Chacón M, Salas M. Safety of Post-Transplant Cyclophosphamide-Based Prophylaxis in AML Patients with Pre-Existing Cardiac Morbidity Undergoing Allogeneic Hematopoietic Cell Transplantation. Cancers. 2025;17(19):3128 [Crossref]
7- Torrent-Rodríguez A, Cascos E, Carcelero E, Riu G, Monge-Escartín I, Ruiz-Boy S, Suárez-Lledó M, Charry P, Cid J, Lozano M, Guardia L, Rosiñol L, Fernández-Avilés F, Martínez C, Carreras E, Rovira M, Salas M. Validation of the CARE-BMT Score and Proposal of a Modified Risk Model With Post-Transplant Cyclofosfamide for Predicting Early Cardiac Events After Allo-HCT. Transplantation and Cellular Therapy. 2026;32(4):478.e1 [Crossref]
8- Wang X, Zhu S, Zhao Y, Di X, Cao L, Reiter R, He E, Zhou Y, Kim B, Cheng Y, Ren J. Pervasive environmental contaminant acrolein compromises myocardial geometry and function through the induction of cuproptosis. ABBS. 2026;58(3):541 [Crossref]
9- Chen T, Lin C, Wang S, Chen C, Lin M, Hsieh C, Lin C, Yeh S, Chiu C. NT-proBNP Levels after First-Dose Post-Transplant Cyclophosphamide Predict Early Cardiac Events and Mortality in Allogeneic Stem Cell Transplantation. Transplantation and Cellular Therapy. 2026;32(5):563.e1 [Crossref]
10- Mao H, Zhao X, Mo S, Wang H, Liu R, Xie Y, Huang Y, Zheng Y, Hua Y. Bone-protective effects of deer-hide gelatin in cyclophosphamide-induced osteoporosis rats. Front Pharmacol. 2025;16 [Crossref]
11- Guida F, Fabi M, Balducci A, Zama D, Masetti R, Mercolini F, Belotti T, Cantarini M, Facchini E, Legnani E, Melchionda F, Bartolacelli Y, Ciuca C, Gesuete V, Prete A, Donti A, Lanari M. Risk Stratification for Cardiotoxicity in Childhood Cancer Survivors: State-of-the-Art Review and a Novel Two-Step Approach. Cancers. 2025;17(23):3740 [Crossref]
12- Ghoflchi S, Vatanparast R, Jalili-Nik M, Kesharwani P, Hosseini H, Sahebkar A. Emerging roles of combined curcumin and berberine in disease modulation: a comprehensive review of mechanisms and therapeutic relevance. Mol Biol Rep. 2026;53(1) [Crossref]
13- Barriga F. Antithymocyte globulin and posttransplant cyclophosphamide in graft vs. host disease prophylaxis: comparison or combination. 2025;32(6):301 [Crossref]
14- He Y, She T, Lin W, Cai S, Cong H, Luo Z. Multiomics Integration and Pharmacovigilance Mining to Decode the Molecular Mechanisms and Biomarkers of Drug‐Induced Hepatic Sinusoidal Obstruction Syndrome. International Journal of Clinical Practice. 2026;2026(1) [Crossref]