Tabriz University of Medical Sciences Journal of Cardiovascular and Thoracic Research 2008-5117 18 1 2026 03 30 Ruptured mitral valve aneurysm in a patient with immunodeficiency and chronic renal failure 66 68 10.34172/jcvtr.026.33214 EN Mustafa Kamil Yemis https://orcid.org/0009-0000-3416-4108 Saadet Guven https://orcid.org/0000-0001-6741-7714 Ozgur Can Usta https://orcid.org/0009-0002-7924-7876 Ahmet Oz https://orcid.org/0000-0003-0268-9641 Turgut Karabag https://orcid.org/0000-0003-3731-8699 Journal Article 10.34172/jcvtr.026.33214 2024 06 09 2025 10 11 Mitral valve aneurysm; defined as a bulge of the mitral valve leaflet toward the left atrium is a rare abnormality whose pathophysiology is poorly understood. The weakened aneurysmal wall may rupture and may cause severe mitral regurgitation and life-threatining conditions. In this case report we present a case of mitral anterior leaflet aneurysm rupture in a patient with immun deficiency and chronic renal failure.